EIF2AK2 anticorps (AA 329-551)

N° du produit ABIN2682988

Détail du produit anti-EIF2AK2 anticorps

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Épitope: AA 329-551

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Fonction: EIF2AK2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli.

Clone: 6H3A10

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: EIF2AK2 (EIF2AK2 Produits)

Synonymes: anticorps PKR, anticorps pkr, anticorps EIF2AK2, anticorps DKFZp469K1934, anticorps EIF2AK1, anticorps PRKR, anticorps 2310047A08Rik, anticorps 4732414G15Rik, anticorps AI467567, anticorps AI747578, anticorps Pkr, anticorps Prkr, anticorps Tik, anticorps eukaryotic translation initiation factor 2 alpha kinase 2, anticorps eukaryotic translation initiation factor 2-alpha kinase 2, anticorps EIF2AK2, anticorps eif2ak2, anticorps Eif2ak2

Sujet:

Description: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Aliases: PKR, PRKR, EIF2AK1

Poids moléculaire: 62kDa

ID gène: 5610

HGNC: 5610

UniProt: P19525

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C