TIE1 anticorps (AA 385-607)

N° du produit ABIN2683015

Détail du produit anti-TIE1 anticorps

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Épitope: AA 385-607

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIE1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Fonction: TIE1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.

Clone: 8D12D2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TIE1

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Autre désignation: TIE1 (TIE1 Produits)

Synonymes: anticorps JTK14, anticorps TIE, anticorps D430008P04Rik, anticorps tie-1, anticorps tyrosine kinase with immunoglobulin like and EGF like domains 1, anticorps tyrosine kinase with immunoglobulin-like and EGF-like domains 1, anticorps tyrosine-protein kinase receptor Tie-1, anticorps endothelium-specific receptor tyrosine kinase 1, anticorps TIE1, anticorps Tie1, anticorps CpipJ_CPIJ018933, anticorps tie1

Sujet:

Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases: TIE, JTK14

Poids moléculaire: 125kDa

ID gène: 7075

HGNC: 7075

UniProt: P35590

Pathways: Signalisation RTK