CD86 anticorps (Biotin)
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- Antigène Voir toutes CD86 Anticorps
- CD86
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD86 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS)
- Marque
- BD Pharmingen™
- Attributs du produit
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2331 (FUN-1) recognizes a 75 kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Cat. No. 555663) recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. 2331 (FUN-1) blocks costimulation activity of CD86 in functional studies. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of Daudi cells analyzed on a FACScan
BD Pharmingen™ Biotin Mouse Anti-Human CD86 - Biotin - Clone 2331 (FUN-1) - Isotype Mouse IgG1, κ - Reactivity Hu - 100 Tests - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Clone
- 2331
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD86 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Volume d'échantillon
- 20 μL
- Restrictions
- For Research Use only
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- Buffer
- Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen." dans: Blood, Vol. 84, Issue 5, pp. 1402-7, (1994) (PubMed).
: "Congenital plasminogen deficiency caused by a Ser572 to Pro mutation." dans: Blood, Vol. 82, Issue 2, pp. 475-80, (1993) (PubMed).
: "A novel monoclonal antibody (FUN-1) identifies an activation antigen in cells of the B-cell lineage and Reed-Sternberg cells." dans: The Journal of pathology, Vol. 169, Issue 3, pp. 309-15, (1993) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
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The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen." dans: Blood, Vol. 84, Issue 5, pp. 1402-7, (1994) (PubMed).
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- Antigène
- CD86
- Autre désignation
- CD86 (CD86 Produits)
- Synonymes
- anticorps B7-2, anticorps B7.2, anticorps B70, anticorps CD28LG2, anticorps LAB72, anticorps B7, anticorps CLS1, anticorps Cd28l2, anticorps ETC-1, anticorps Ly-58, anticorps Ly58, anticorps MB7, anticorps MB7-2, anticorps TS/A-2, anticorps CD86 molecule, anticorps CD86 antigen, anticorps integrin subunit alpha 2b, anticorps CD86, anticorps Cd86, anticorps Itga2b
- Sujet
- Synonyms: B70/B7-2
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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