Chondroitin Sulfate anticorps

N° du produit ABIN2689471

Détail du produit anti-Chondroitin Sulfate anticorps

Antigène: Chondroitin Sulfate (CS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Chondroitin Sulfate est non-conjugé

Application: Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: The 9.2.27 monoclonal antibody specifically binds to CSPG4 (chondroitin sulfate proteoglycan 4). CSPG4 is also known as MCSP (melanoma chondroitin sulfate proteoglycan) and NG2 (neural/glial antigen 2). The hybridoma secreting the 9.2.27 antibody was generated using a human melanoma cell extract as the immunogen. Tumor cells display a variety of antigens which have been defined by antibodies. Antibodies that specifically react with tumor-associated antigens are useful in understanding the biology of particular tumor types. Proteoglycans including chondroitin sulfate, keratan sulfate, dermatan sulfate and heparan sulfate are major components of the extracellular matrices of many animal cell types.

BD Pharmingen™ Purified Mouse Anti-Chondroitin Sulfate - Purified - Clone 9.2.27 - Isotype Mouse IgG2a - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Extracts of Human M21 Melanoma Cells

Clone: 9-2-27

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-Chondroitin Sulfate (ABIN2689471)

Schrappe, Bumol, Apelgren, Briggs, Koppel, Markowitz, Mueller, Reisfeld: "Long-term growth suppression of human glioma xenografts by chemoimmunoconjugates of 4-desacetylvinblastine-3-carboxyhydrazide and monoclonal antibody 9.2.27." dans: Cancer research, Vol. 52, Issue 14, pp. 3838-44, (1992) (PubMed).

Cheresh, Honsik, Staffileno, Jung, Reisfeld: "Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 15, pp. 5155-9, (1985) (PubMed).

Bumol, Walker, Reisfeld: "Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans." dans: The Journal of biological chemistry, Vol. 259, Issue 20, pp. 12733-41, (1984) (PubMed).

Morgan, Galloway, Reisfeld: "Production and characterization of monoclonal antibody to a melanoma specific glycoprotein." dans: Hybridoma, Vol. 1, Issue 1, pp. 27-36, (1984) (PubMed).

Bumol, Reisfeld: "Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 4, pp. 1245-9, (1982) (PubMed).

Détails sur Chondroitin Sulfate

Antigène: Chondroitin Sulfate (CS)

Autre désignation: Chondroitin Sulfate (CS Produits)

Sujet: Synonyms: CSPG4, NG2, Chondroitin sulfate proteoglycan 4, MCSP, MCSPG, MELCSPG, MSK16