FAIM3 anticorps (AA 51-150) (Biotin)

N° du produit ABIN2690130

Détail du produit anti-FAIM3 anticorps (Biotin)

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Épitope: AA 51-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAIM3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FAIM3

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Autre désignation: FAIM3 (FAIM3 Produits)

Synonymes: anticorps FAIM3, anticorps FCMR, anticorps TOSO, anticorps 1810037B05Rik, anticorps FcmuR, anticorps Toso, anticorps Fc fragment of IgM receptor, anticorps FCMR, anticorps Fcmr

Sujet:

Synonyms: TOSO, FAIM3, Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

ID gène: 9214

UniProt: O60667