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p53 anticorps

GMP Grade TP53 Reactivité: Humain WB Hôte: Souris Monoclonal PAB122 unconjugated
N° du produit ABIN2704417
  • Antigène Voir toutes p53 (TP53) Anticorps
    p53 (TP53) (Tumor Protein P53 (TP53))
    Reactivité
    • 863
    • 259
    • 216
    • 116
    • 50
    • 35
    • 33
    • 19
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 648
    • 231
    • 6
    • 2
    • 1
    Souris
    Clonalité
    • 602
    • 285
    • 1
    Monoclonal
    Conjugué
    • 488
    • 43
    • 39
    • 25
    • 22
    • 14
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp p53 est non-conjugé
    Application
    • 698
    • 334
    • 249
    • 219
    • 194
    • 146
    • 125
    • 124
    • 119
    • 68
    • 54
    • 35
    • 18
    • 17
    • 13
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Anti-p53 Unconjugated Antibody
    Attributs du produit
    p53, a DNA-binding, oligomerization domain- and transcription activation domaincontaining tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    SV40-transformed, 3T3 clone 4 mouse cells
    Clone
    PAB122
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product TP53 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    p53 (TP53) (Tumor Protein P53 (TP53))
    Autre désignation
    p53 (TP53 Produits)
    Synonymes
    anticorps BCC7, anticorps LFS1, anticorps P53, anticorps TRP53, anticorps p53, anticorps Trp53, anticorps brp53, anticorps drp53, anticorps etID22686.5, anticorps fb40d06, anticorps wu:fb40d06, anticorps zgc:111919, anticorps Tp53, anticorps bbl, anticorps bfy, anticorps bhy, anticorps p44, anticorps tp53, anticorps Xp53, anticorps TP53, anticorps tumor protein p53, anticorps cellular tumor antigen p53, anticorps transformation related protein 53, anticorps tumor protein p53 L homeolog, anticorps TP53, anticorps CpipJ_CPIJ002758, anticorps Tp53, anticorps tp53, anticorps Trp53, anticorps tp53.L
    NCBI Accession
    NM_000546
    UniProt
    P04637
    Pathways
    Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
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