Aminoacylase 1 anticorps
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- Antigène Voir toutes Aminoacylase 1 (ACY1) Anticorps
- Aminoacylase 1 (ACY1)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Aminoacylase 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Attributs du produit
- Homo sapiens aminoacylase 1 (ACY1), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human ACY1(NP_000657) produced in HEK293 cell.
- Clone
- 16C1
- Isotype
- IgG1
- Top Product
- Discover our top product ACY1 Anticorps primaire
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- Indications d'application
- WB 1:500, IHC 1:150, FLOW 1:100,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- Aminoacylase 1 (ACY1)
- Autre désignation
- ACY1 (ACY1 Produits)
- Synonymes
- anticorps si:zfos-226g1.1, anticorps zgc:55605, anticorps zgc:76955, anticorps acy1, anticorps acy1d, anticorps acylase, anticorps ACY1, anticorps ACY-1, anticorps ACY1D, anticorps 1110014J22Rik, anticorps Acy-1, anticorps Acy1a, anticorps Acy1b, anticorps aminoacylase 1, anticorps aminoacylase 1, gene 1 S homeolog, anticorps aminoacylase 1, gene 1, anticorps ACY1, anticorps acy1, anticorps acy1.1.S, anticorps acy1.1, anticorps Acy1
- Sujet
- This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
- Poids moléculaire
- 45.7 kDa
- ID gène
- 95
- NCBI Accession
- NM_000666
- HGNC
- 95
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