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FGFR2 anticorps

FGFR2 Reactivité: Humain WB, FACS, IF Hôte: Souris Monoclonal 5F7 unconjugated
N° du produit ABIN2717921
  • Antigène Voir toutes FGFR2 Anticorps
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Reactivité
    • 136
    • 71
    • 50
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 123
    • 12
    • 1
    Souris
    Clonalité
    • 115
    • 21
    Monoclonal
    Conjugué
    • 57
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FGFR2 est non-conjugé
    Application
    • 79
    • 55
    • 47
    • 40
    • 29
    • 17
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
    Attributs du produit
    Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogène
    Full length human recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cell.
    Clone
    5F7
    Isotype
    IgG2a
    Top Product
    Discover our top product FGFR2 Anticorps primaire
  • Indications d'application
    WB 1:2000, IF 1:100, FLOW 1:100
    Commentaires

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Autre désignation
    FGFR2 (FGFR2 Produits)
    Synonymes
    anticorps FGFR2, anticorps FGFR2IIIb, anticorps bek, anticorps bfr-1, anticorps cd332, anticorps cek3, anticorps cfd1, anticorps ect1, anticorps fgfr-2, anticorps jws, anticorps k-sam, anticorps kgfr, anticorps tk14, anticorps tk25, anticorps xfgfr2, anticorps DKFZp469H1521, anticorps BBDS, anticorps BEK, anticorps BFR-1, anticorps CD332, anticorps CEK3, anticorps CFD1, anticorps ECT1, anticorps JWS, anticorps K-SAM, anticorps KGFR, anticorps TK14, anticorps TK25, anticorps AU043015, anticorps AW556123, anticorps Bek, anticorps Fgfr-2, anticorps Fgfr-7, anticorps Fgfr7, anticorps KGFRTr, anticorps svs, anticorps FGF-R, anticorps fgfr72IIIb, anticorps FGFR, anticorps fc56c05, anticorps wu:fc56c05, anticorps fibroblast growth factor receptor 2, anticorps fibroblast growth factor receptor 2 L homeolog, anticorps FGFR2, anticorps LOC100084641, anticorps fgfr2, anticorps Fgfr2, anticorps fgfr2.L
    Sujet
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Poids moléculaire
    89.7 kDa
    ID gène
    2263
    NCBI Accession
    NM_000141
    HGNC
    2263
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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