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MAP2K4 anticorps
MAP2K4
Reactivité: Humain, Souris
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-MAP2K4 anticorps
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Antigène
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MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
Reactivité
Toutes les réactivités sur MAP2K4 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur MAP2K4 Anticorps
Lapin
Clonalité
Toutes les clonalités sur MAP2K4 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers MAP2K4 Anticorps
Cet anticorp MAP2K4 est non-conjugé
Application
Tous les applications à travers MAP2K4 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody detects endogenous levels of SEK1/MKK4 protein. (region surrounding Glu74)
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Pureté
> 95 % pure by SDS-PAGE
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Information d'application
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Indications d'application
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
DO NOT FREEZE!
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Détails sur MAP2K4
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Antigène
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
Autre désignation
MAP2K4 (MAP2K4 Produits )
Synonymes
anticorps JNKK, anticorps JNKK1, anticorps MAPKK4, anticorps MEK4, anticorps MKK4, anticorps PRKMK4, anticorps SAPKK-1, anticorps SAPKK1, anticorps SEK1, anticorps SERK1, anticorps SKK1, anticorps Sek1, anticorps Serk1, anticorps MKK4A-l, anticorps map2k4, anticorps zgc:136500, anticorps jnkk, anticorps mek4, anticorps mkk4, anticorps sek1, anticorps jnkk1, anticorps serk1, anticorps xmek2, anticorps mapkk4, anticorps prkmk4, anticorps 142758_at, anticorps CG9738, anticorps CT27508, anticorps D-MKK4, anticorps DMKK4, anticorps Dmel\\CG9738, anticorps JNKK2, anticorps Mpk4, anticorps SEK1/MKK4, anticorps dMKK4, anticorps dMkk4, anticorps hep, anticorps ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, anticorps ATMEK4, anticorps ATMKK4, anticorps F19C24.26, anticorps F19C24_26, anticorps MAP KINASE KINASE 4, anticorps mitogen-activated protein kinase kinase 4, anticorps MKK4B, anticorps zgc:194486, anticorps mitogen-activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4a, anticorps MAP kinase kinase 4, anticorps mitogen activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4b, anticorps MAP2K4, anticorps Map2k4, anticorps map2k4a, anticorps map2k4, anticorps Mkk4, anticorps MKK4, anticorps map2k4b
Sujet
The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.Synonyms: Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAP Kinase Kinase 4, MAPKK4, MEK-4, MKK4, PRKMK4, SAPK/ERK kinase 1, SERK1, c-Jun N-terminal kinase kinase 1
Poids moléculaire
approx. 44 kDa
ID gène
6416
NCBI Accession
NP_003001
UniProt
P45985
Pathways
Signalisation MAPK , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , BCR Signaling
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