IRF2 anticorps
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- Antigène Voir toutes IRF2 Anticorps
- IRF2 (Interferon Regulatory Factor 2 (IRF2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of IRF-2 protein. (region surrounding Lys129)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography using epitope-specific immunogen.
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- Discover our top product IRF2 Anticorps primaire
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- Indications d'application
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ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- IRF2 (Interferon Regulatory Factor 2 (IRF2))
- Autre désignation
- IRF2 (IRF2 Produits)
- Synonymes
- anticorps IRF-2, anticorps 9830146E22Rik, anticorps AI646973, anticorps Irf-2, anticorps irf2b, anticorps zgc:103451, anticorps irf-2, anticorps wu:fc74h04, anticorps zgc:76951, anticorps interferon regulatory factor 2, anticorps interferon regulatory factor 2 L homeolog, anticorps interferon regulatory factor 2a, anticorps IRF2, anticorps Irf2, anticorps irf2, anticorps irf2.L, anticorps irf2a
- Sujet
- Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).Synonyms: IRF-2, Interferon regulatory factor 2
- Poids moléculaire
- approx. 47 kDa
- ID gène
- 3660
- NCBI Accession
- NP_002190
- UniProt
- P14316
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