FXR2 anticorps
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- Antigène Voir toutes FXR2 Anticorps
- FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FXR2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of FXR2 protein. (region surrounding Glu576)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- Affinity-Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product FXR2 Anticorps primaire
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- Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))
- Autre désignation
- FXR2 (FXR2 Produits)
- Synonymes
- anticorps id:ibd5046, anticorps zgc:56215, anticorps zgc:77472, anticorps FMR1L2, anticorps FXR2P, anticorps Fxr2h, anticorps FMR1 autosomal homolog 2, anticorps fragile X mental retardation, autosomal homolog 2, anticorps FXR2, anticorps fxr2, anticorps Fxr2
- Sujet
- Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene, and in the fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 can also interact with two fragile X syndrome related factors, FXR1 and FXR2, and these proteins form heterodimers through their N-terminal coilcoiled domains. FMR1 localizes to both the nucleus and the cytoplasm, and since it contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleo-cytoplasmic transport of mRNAs.Synonyms: FMR1L2, Fragile X mental retardation syndrome-related protein 2
- Poids moléculaire
- approx. 65 kDa
- ID gène
- 9513
- NCBI Accession
- NP_004851
- UniProt
- P51116
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