14-3-3 theta anticorps
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- Antigène Voir toutes 14-3-3 theta (YWHAQ) Anticorps
- 14-3-3 theta (YWHAQ)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp 14-3-3 theta est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of 14-3-3 θ protein. (region surrounding Gln67)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product YWHAQ Anticorps primaire
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- Indications d'application
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- 14-3-3 theta (YWHAQ)
- Autre désignation
- 14-3-3 Protein theta (YWHAQ Produits)
- Synonymes
- anticorps 14-3-3, anticorps 14-3-3t, anticorps 1c5, anticorps hs1, anticorps 1C5, anticorps HS1, anticorps 2700028P07Rik, anticorps AA409740, anticorps AU021156, anticorps R74690, anticorps ywhaq, anticorps ywhaq2, anticorps wu:fa91b01, anticorps wu:fb02e12, anticorps wu:fb36f06, anticorps wu:fk86h02, anticorps ywhaq1, anticorps ywhaz, anticorps zgc:55499, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta S homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a, anticorps 14-3-3 protein theta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b, anticorps YWHAQ, anticorps ywhaq, anticorps Ywhaq, anticorps ywhaq.S, anticorps ywhaqa, anticorps ywhaqb
- Sujet
- 14-3-3 proteins regulate many cellular processes relevant to cancer biology,notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activitiesSynonyms: 14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1, YWHAQ
- Poids moléculaire
- approx. 28 kDa
- ID gène
- 10971
- NCBI Accession
- NP_006817
- UniProt
- P27348
- Pathways
- Apoptose, Myometrial Relaxation and Contraction
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