PDE4B anticorps
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- Antigène Voir toutes PDE4B Anticorps
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PDE4B est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Attributs du produit
- Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
- Clone
- 1D12
- Isotype
- IgG1
- Top Product
- Discover our top product PDE4B Anticorps primaire
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- Indications d'application
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." dans: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
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AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." dans: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
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- Antigène
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- Autre désignation
- PDE4B (PDE4B Produits)
- Synonymes
- anticorps dpde4, anticorps pde4b5, anticorps pdeivb, anticorps Dpde4, anticorps R74983, anticorps dunce, anticorps PDE4/IVb, anticorps Pde4B1, anticorps Pde4B2, anticorps Pde4B3, anticorps Pde4B4, anticorps DPDE4, anticorps PDE4B5, anticorps PDEIVB, anticorps phosphodiesterase 4B, anticorps phosphodiesterase 4B, cAMP specific, anticorps phosphodiesterase 4B S homeolog, anticorps pde4b, anticorps PDE4B, anticorps Pde4b, anticorps pde4b.S
- Sujet
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Poids moléculaire
- 83.2 kDa
- ID gène
- 5142
- NCBI Accession
- NM_002600
- HGNC
- 5142
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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