PSMA anticorps
-
- Antigène Voir toutes PSMA (FOLH1) Anticorps
- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
-
Reactivité
- Humain, Souris
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp PSMA est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Attributs du produit
- Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.
- Clone
- 3H5
- Isotype
- IgG1
- Top Product
- Discover our top product FOLH1 Anticorps primaire
-
-
- Indications d'application
- WB 1:500~1000, IHC 1:150, IF 1:100, FLOW 1:100,
- Commentaires
-
The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
-
- Antigène
- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
- Autre désignation
- FOLH1 (FOLH1 Produits)
- Synonymes
- anticorps FGCP, anticorps FOLH, anticorps GCP2, anticorps GCPII, anticorps NAALAD1, anticorps NAALAdase, anticorps PSM, anticorps PSMA, anticorps mGCP, anticorps mopsm, anticorps Naalad, anticorps putative N-acetylated-alpha-linked acidic dipeptidase, anticorps folate hydrolase 1B, anticorps folate hydrolase 1, anticorps folate hydrolase (prostate-specific membrane antigen) 1, anticorps LOC451185, anticorps FOLH1B, anticorps FOLH1, anticorps Folh1
- Sujet
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Poids moléculaire
- 84.2 kDa
- ID gène
- 2346
- NCBI Accession
- NM_004476
- HGNC
- 2346
-