RASSF1 anticorps
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- Antigène Voir toutes RASSF1 Anticorps
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RASSF1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Attributs du produit
- Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
- Clone
- 2A9
- Isotype
- IgG1
- Top Product
- Discover our top product RASSF1 Anticorps primaire
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- Indications d'application
- WB 1:500, IF 1:100, FLOW 1:100
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Autre désignation
- RASSF1 (RASSF1 Produits)
- Synonymes
- anticorps RASSF1, anticorps zgc:92505, anticorps wu:fc17f02, anticorps zgc:112224, anticorps 123F2, anticorps NORE2A, anticorps RASSF1A, anticorps RDA32, anticorps REH3P21, anticorps AA536941, anticorps AU044980, anticorps Rassf1A, anticorps Rassf1B, anticorps Rassf1C, anticorps NPR2-like, GATOR1 complex subunit, anticorps Ras association (RalGDS/AF-6) domain family 1, anticorps Ras association domain family member 1, anticorps putative rassf1, anticorps Ras association domain family member 1 L homeolog, anticorps Ras association (RalGDS/AF-6) domain family member 1, anticorps NPRL2, anticorps rassf1, anticorps RASSF1, anticorps Smp_157340, anticorps rassf1.L, anticorps Rassf1
- Sujet
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Poids moléculaire
- 38.6 kDa
- ID gène
- 11186
- NCBI Accession
- NM_007182
- HGNC
- 28844
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