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Cytokeratin 8/18 anticorps

Reactivité: Humain WB, FACS, IF, IHC (p), IHC, IP Hôte: Souris Monoclonal K8-8-DC10 unconjugated
N° du produit ABIN2740299
  • Antigène Tous les produits Cytokeratin 8/18
    Cytokeratin 8/18
    Reactivité
    • 42
    • 10
    • 9
    • 9
    • 9
    • 8
    Humain
    Hôte
    • 34
    • 8
    • 1
    Souris
    Clonalité
    • 42
    • 1
    Monoclonal
    Conjugué
    • 11
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cytokeratin 8/18 est non-conjugé
    Application
    • 32
    • 31
    • 31
    • 14
    • 11
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Specificité
    Human Cytokeratin 8+18
    Purification
    Protein G purified
    Immunogène
    A keratin preparation from a human carcinoma (K8.8) and PMC-42 human breast carcinoma cells (DC10) were used as the immunogen for this Cytokeratin 8 + 18 antibody cocktail.

    Type of Immunogen: Cells
    Clone
    K8-8-DC10
    Isotype
    IgG1 kappa
  • Indications d'application
    Approved: Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: Cytokeratins are a group of proteins expressed in pairs in keratinized and non-keratinized epithelial tissue. Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). The pair are normally seen in simple but not stratified epithelial cells. This antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. Immunohistochemical staining with this antibody cocktail is indistinguishable from that obtained with monoclonal antibody 5D3.
    Commentaires

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2°C to 8°C.
  • Antigène
    Cytokeratin 8/18
    Autre désignation
    Cytokeratin 8+18 (Cytokeratin 8/18 Produits)
    Sujet
    This antibody detects: Cytokeratin 8+18
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