XRCC6/XRCC5 anticorps
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- Antigène Tous les produits XRCC6/XRCC5
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- Reactivité
- Humain, Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp XRCC6/XRCC5 est non-conjugé
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Specificité
- Human Ku70+Ku80 / XRCC6+XRCC5
- Aucune reactivité croisée
- Poulet, Souris, Rat (Rattus)
- Purification
- Protein G purified
- Immunogène
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Nuclear extract of human HL-60 cells.
Type of Immunogen: Cells - Clone
- KU729
- Isotype
- IgG1 kappa
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- Indications d'application
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Approved: Flo (0.5 - 1 μg/10 x106), ICC (0.25 - 0.5 μg/mL), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP
Usage: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Immunocytochemistry (Acetone-fixed cells) : 0.25-0.5 μg/mL for 30 minutes at RT. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2°C to 8°C.
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- Antigène
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- Autre désignation
- Ku70+Ku80 / XRCC6+XRCC5 (XRCC6/XRCC5 Produits)
- Sujet
- This antibody detects: Ku70+Ku80 / XRCC6+XRCC5
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