BMF anticorps (AA 13-27, AA 112-126)

N° du produit ABIN2745519

Détail du produit anti-BMF anticorps

Antigène: BMF (Bcl2 Modifying Factor (BMF))

Épitope: AA 13-27, AA 112-126

Reactivité: Souris, Rat

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BMF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Specificité: Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25 kDa and ~30 kDa by Western blot, corresponding to endogenous Bmf and BmfL.

Réactivité croisée: Souris, Rat (Rattus)

Aucune reactivité croisée: Humain

Réactivité croisée (Details): Does not cross-react with human Bmf.

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.1EU/μg purified protein (LAL test, Lonza).

Immunogène: Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.

Clone: 17A9

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur BMF

Antigène: BMF (Bcl2 Modifying Factor (BMF))

Autre désignation: Bmf (BMF Produits)

Synonymes: anticorps BMF, anticorps AW260063, anticorps AW411872, anticorps Bcl2 modifying factor, anticorps Bcl2 modifying factor L homeolog, anticorps BCL2 modifying factor, anticorps BMF, anticorps bmf.L, anticorps Bmf

Sujet: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

UniProt: Q91ZE9