PDE1C anticorps (N-Term)

N° du produit ABIN2747083

Détail du produit anti-PDE1C anticorps

Antigène: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE1C est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Purification: Affinity Purified

Immunogène: Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.75-1.25 μg/μL

Références pour anticorps anti-PDE1C (ABIN2747083)

Cesarini, Martini, Vitiani, Gravina, Di Agostino, Graziani, DAlessandris, Pallini, Larocca, Rossi, Jannini, Dolci: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." dans: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." dans: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." dans: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." dans: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." dans: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." dans: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Dong, Zitt, Auriga, Hatzelmann, Epstein: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." dans: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).

Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." dans: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

Dunkern, Hatzelmann: "Characterization of inhibitors of phosphodiesterase 1C on a human cellular system." dans: The FEBS journal, Vol. 274, Issue 18, pp. 4812-24, (2007) (PubMed).

Baxendale, Fraser: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." dans: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).

Dolci, Belmonte, Santone, Giorgi, Pellegrini, Carosa, Piccione, Lenzi, Jannini: "Subcellular localization and regulation of type-1C and type-5 phosphodiesterases." dans: Biochemical and biophysical research communications, Vol. 341, Issue 3, pp. 837-46, (2006) (PubMed).

Santone, Giorgi, Maccarone, Basso, Deplano, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina." dans: Journal of neuroscience research, Vol. 84, Issue 5, pp. 1020-6, (2006) (PubMed).

Détails sur PDE1C

Antigène: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Autre désignation: PDE1C (PDE1C Produits)

Synonymes: anticorps CG14940, anticorps CG14942, anticorps CG14943, anticorps CG14944, anticorps CG31757, anticorps CG31758, anticorps CG42325, anticorps CG44007, anticorps Dmel\\CG44007, anticorps Dmel_CG14940, anticorps Dmel_CG14943, anticorps Dmel_CG14944, anticorps Dmel_CG31757, anticorps Dmel_CG31758, anticorps Dmel_CG42325, anticorps PDE1C, anticorps PDE1c, anticorps GB13690, anticorps Hcam3, anticorps Phosphodiesterase 1c, anticorps phosphodiesterase 1C, anticorps calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, anticorps calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, anticorps phosphodiesterase 1C, calmodulin-dependent b, anticorps Pde1c, anticorps PDE1C, anticorps LOC724389, anticorps LOC100019026, anticorps pde1cb

NCBI Accession: XP_004857

UniProt: Q14123

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma