PDE3A anticorps

N° du produit ABIN2747088

Détail du produit anti-PDE3A anticorps

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Reactivité: Humain, Rat, Souris, Singe, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE3A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Purification: Affinity Purified

Immunogène: Synthetic peptide selective only for PDE3A variants

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 μg/μL

Références pour anticorps anti-PDE3A (ABIN2747088)

Fields, Koschinski, Zaccolo: "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." dans: Cellular signalling, Vol. 28, Issue 7, pp. 725-32, (2017) (PubMed).

Yang, Kirton, MacDougall, Boyle, Deuchars, Frater, Ponnambalam, Hardy, White, Calaghan, Peers, Steele: "The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway." dans: Science signaling, Vol. 8, Issue 398, pp. ra101, (2016) (PubMed).

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." dans: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." dans: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." dans: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." dans: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

Ückert, Waldkirch, Sonnenberg, Sandner, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." dans: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).

Nishioka, Nishida, Ariyoshi, Jian, Saiki, Hirano, Nakaya, Sato, Kita, Iwamoto, Hirano, Inoue, Kurose: "Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 31, Issue 10, pp. 2278-86, (2011) (PubMed).

Dov, Abramovitch, Warwar, Nesher: "Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose." dans: Endocrinology, Vol. 149, Issue 2, pp. 741-8, (2008) (PubMed).

Dony, Lai, Dumitrascu, Pullamsetti, Savai, Ghofrani, Weissmann, Schudt, Flockerzi, Seeger, Grimminger, Schermuly: "Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition." dans: The European respiratory journal, Vol. 31, Issue 3, pp. 599-610, (2008) (PubMed).

Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." dans: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

Albrecht, Uckert, Oelke, Andersson, Jonas, Tröger, Hedlund: "Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human vagina: a potential forensic value?" dans: Journal of forensic and legal medicine, Vol. 14, Issue 5, pp. 270-4, (2007) (PubMed).

Ückert, Oelke, Albrecht, Stief, Jonas, Hedlund: "Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora." dans: The journal of sexual medicine, Vol. 4, Issue 3, pp. 602-608, (2007) (PubMed).

Oelke, Hedlund, Albrecht, Ellinghaus, Stief, Jonas, Andersson, Uckert: "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study." dans: Urology, Vol. 67, Issue 5, pp. 1111-6, (2006) (PubMed).

Uckert, Hedlund, Waldkirch, Sohn, Jonas, Andersson, Stief: "Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone." dans: World journal of urology, Vol. 22, Issue 4, pp. 261-6, (2005) (PubMed).

Netherton, Maurice: "Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis." dans: Molecular pharmacology, Vol. 67, Issue 1, pp. 263-72, (2005) (PubMed).

Uckert, Oelke, Waldkirch, Stief, Albrecht, Tröger, Jonas, Andersson, Hedlund: "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." dans: Urology, Vol. 65, Issue 3, pp. 604-10, (2005) (PubMed).

Mongillo, McSorley, Evellin, Sood, Lissandron, Terrin, Huston, Hannawacker, Lohse, Pozzan, Houslay, Zaccolo: "Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases." dans: Circulation research, Vol. 95, Issue 1, pp. 67-75, (2004) (PubMed).

Détails sur PDE3A

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Autre désignation: PDE3A (PDE3A Produits)

Synonymes: anticorps PDE3A, anticorps Pde3a, anticorps si:dkey-48h7.2, anticorps A930022O17Rik, anticorps C87899, anticorps RNPDE3A, anticorps CGI-PDE, anticorps CGI-PDE A, anticorps CGI-PDE-A, anticorps phosphodiesterase 3A, anticorps phosphodiesterase 3A, cGMP-inhibited, anticorps cGMP-inhibited 3',5'-cyclic phosphodiesterase A, anticorps phosphodiesterase 3A, cGMP inhibited, anticorps PDE3A, anticorps Pde3a, anticorps LOC100540515, anticorps pde3a

NCBI Accession: NP_000912

UniProt: Q14432

Pathways: cAMP Metabolic Process