CD2 anticorps
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- Antigène Voir toutes CD2 Anticorps
- CD2
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD2 est non-conjugé
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificité
- The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- niveau d'endotoxine
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- Immunogène
- Cytotoxic T lymphocytes
- Clone
- TS1-8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD2 Anticorps primaire
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- Indications d'application
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." dans: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." dans: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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- Antigène
- CD2
- Autre désignation
- CD2 (CD2 Produits)
- Synonymes
- anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2
- Sujet
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- ID gène
- 914
- UniProt
- P06729
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