Sialoadhesin/CD169 anticorps

N° du produit ABIN2749048

Détail du produit anti-Sialoadhesin/CD169 anticorps

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Sialoadhesin/CD169 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: The mouse monoclonal antibody 7-239 recognizes an extracellular epitope of CD169 (sialoadhesin, Siglec-1), a 210 kDa type I transmembrane glycoprotein expressed on macrophages and dendritic cells.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: human rhinovirus 14-infected monocyte-derived dendritic cells

Clone: 7-239

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Sialoadhesin/CD169

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Autre désignation: CD169 / Siglec-1 (SIGLEC1 Produits)

Synonymes: anticorps Cd169, anticorps Siglec-1, anticorps Sn, anticorps CD169, anticorps SIGLEC-1, anticorps SN, anticorps dJ1009E24.1, anticorps SA, anticorps SIGLEC1, anticorps p210, anticorps pSn, anticorps sialic acid binding Ig like lectin 1, anticorps sialic acid binding Ig-like lectin 1, sialoadhesin, anticorps SIGLEC1, anticorps Siglec1

Sujet: Sialic acid binding Ig like lectin 1,CD169, also known as Siglec-1 or sialoadhesin, is a type I transmembrane glycoprotein of the sialic acid binding Ig-like lectin family. It binds to sialylated glycoproteins on various haematopoietic cells to mediate cell-cell interactions. CD169 is expressed on a subset of macrophages and dendritic cells. On CD14+ monocytes its expression can be induced by interferon alpha and gamma. High expression of CD169 is observed in the spleen, lymph nodes, bone marrow, and under inflammatory conditions rheumatoid arthritis and atherosclerosis, lower in the liver, lungs and gut. It has been shown to be involved in antigen presentation to invariant NKT cells, which play an important role in the innate arm of the immune system to modulate the subsequent acquired immune responses.,SIGLEC1, SN, sialoadhesin

ID gène: 6614

UniProt: Q9BZZ2