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PCLO anticorps

PCLO Reactivité: Humain WB, FACS Hôte: Souris Monoclonal PCLO-01 unconjugated
N° du produit ABIN2749094
  • Antigène Voir toutes PCLO Anticorps
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Reactivité
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 6
    • 1
    Souris
    Clonalité
    • 4
    • 3
    Monoclonal
    Conjugué
    • 5
    • 2
    Cet anticorp PCLO est non-conjugé
    Application
    • 6
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Human recombinant PCLO protein
    Clone
    PCLO-01
    Isotype
    IgG1
    Top Product
    Discover our top product PCLO Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-5 μg/mL, intracellular staining.
    Western blotting: A small splice variant of PCLO can be analyzed by Western blotting, however, the whole protein is too large (over 400 kDa) to be successfully processed by SDS PAAGE.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Autre désignation
    PCLO (PCLO Produits)
    Synonymes
    anticorps pclo, anticorps wu:fj53e09, anticorps Acz, anticorps Pico, anticorps mKIAA0559, anticorps aczonin, anticorps PCLO, anticorps ACZ, anticorps piccolo presynaptic cytomatrix protein, anticorps piccolo presynaptic cytomatrix protein a, anticorps piccolo (presynaptic cytomatrix protein), anticorps PCLO, anticorps pcloa, anticorps Pclo, anticorps LOC768552
    Sujet
    Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin
    ID gène
    27445
    UniProt
    Q9Y6V0
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
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