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PCLO anticorps (PE)

PCLO Reactivité: Humain FACS Hôte: Souris Monoclonal PCLO-01 PE
N° du produit ABIN2749163
  • Antigène Voir toutes PCLO Anticorps
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Reactivité
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 6
    • 1
    Souris
    Clonalité
    • 4
    • 3
    Monoclonal
    Conjugué
    • 6
    • 1
    Cet anticorp PCLO est conjugé à/à la PE
    Application
    • 7
    • 3
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human recombinant PCLO protein
    Clone
    PCLO-01
    Isotype
    IgG1
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Autre désignation
    PCLO (PCLO Produits)
    Synonymes
    anticorps pclo, anticorps wu:fj53e09, anticorps Acz, anticorps Pico, anticorps mKIAA0559, anticorps aczonin, anticorps PCLO, anticorps ACZ, anticorps piccolo presynaptic cytomatrix protein, anticorps piccolo presynaptic cytomatrix protein a, anticorps piccolo (presynaptic cytomatrix protein), anticorps PCLO, anticorps pcloa, anticorps Pclo, anticorps LOC768552
    Sujet
    Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin
    ID gène
    27445
    UniProt
    Q9Y6V0
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
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