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TCR alpha/beta anticorps (PerCP)

TCR alpha/beta Reactivité: Humain FACS Hôte: Souris Monoclonal IP26 PerCP
N° du produit ABIN2749164
  • Antigène Tous les produits TCR alpha/beta
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Reactivité
    • 19
    • 18
    • 14
    • 7
    • 6
    • 4
    • 3
    • 1
    Humain
    Hôte
    • 45
    • 12
    Souris
    Clonalité
    • 57
    Monoclonal
    Conjugué
    • 17
    • 10
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCR alpha/beta est conjugé à/à la PerCP
    Application
    • 51
    • 31
    • 29
    • 20
    • 18
    • 9
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody IP26 recognizes a monomorphic extracellular determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Clone
    IP26
    Isotype
    IgG1
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." dans: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

    Ortonne, Huet, Gaudez, Marie-Cardine, Schiavon, Bagot, Musette, Bensussan: "Significance of circulating T-cell clones in Sezary syndrome." dans: Blood, Vol. 107, Issue 10, pp. 4030-8, (2006) (PubMed).

    Huet, Bagot, Loyaux, Capdevielle, Conraux, Ferrara, Bensussan, Marie-Cardine: "SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 1, pp. 652-9, (2005) (PubMed).

  • Antigène
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Autre désignation
    TCR alpha/beta (TCR alpha/beta Produits)
    Sujet
    The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
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