PDE5A anticorps (phosphorylated)

N° du produit ABIN2750986

Détail du produit anti-PDE5A anticorps

Antigène: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Épitope: AA 120-170, phosphorylated

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE5A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purification: Affinity Purified

Immunogène: Phosphorylated synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0-1.25 μg/μL

Références pour anticorps anti-PDE5A (ABIN2750986)

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." dans: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Bautista Niño, Durik, Danser, de Vries, Musterd-Bhaggoe, Meima, Kavousi, Ghanbari, Hoeijmakers, ODonnell, Franceschini, Janssen, De Mey, Liu, Shanahan, Franco, Dehghan, Roks: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." dans: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, (2015) (PubMed).

Luong, Rey-Perra, Vadivel, Gilmour, Sauve, Koonen, Walker, Todd, Gressens, Kassiri, Nadeem, Morgan, Eaton, Dyck, Archer, Thébaud: "Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia." dans: Circulation, Vol. 123, Issue 19, pp. 2120-31, (2011) (PubMed).

Monfort, Muñoz, Felipo: "Chronic hyperammonemia in vivo impairs long-term potentiation in hippocampus by altering activation of cyclic GMP-dependent-protein kinase and of phosphodiesterase 5." dans: Journal of neurochemistry, Vol. 94, Issue 4, pp. 934-42, (2005) (PubMed).

Détails sur PDE5A

Antigène: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Autre désignation: PDE5A (PDE5A Produits)

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling