NR3C2 anticorps (Middle Region)
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- Antigène Voir toutes NR3C2 Anticorps
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cheval, Boeuf (Vache), Porc, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR3C2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- RRKNCPACRL QKCLQAGMNL GARKSKKLGK LKGIHEEQPQ QQQPPPPPPP
- Homologie
- Cow: 83%, Guinea Pig: 75%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR3C2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human NR3C2
- Top Product
- Discover our top product NR3C2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 984 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Autre désignation
- NR3C2 (NR3C2 Produits)
- Synonymes
- anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L
- Sujet
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NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Alias Symbols: MCR, MGC133092, MLR, MR, NR3C2VIT
Protein Interaction Partner: RABAC1, RXRA, HSP90AA1, ACSL1, UBC, SRC, PPP5C, PPID, FKBP5, FKBP4, STUB1, AIP, TRIM24, NRIP1, DNAJC7, CAND1, SUMO1, UBE2I, EIF3I, PROX1, PIAS1, PIAS3, HSPA4, PTGES3, AR, NR3C1, ACTA1, ACTG1,
Protein Size: 984 - Poids moléculaire
- 107 kDa
- ID gène
- 4306
- NCBI Accession
- NM_000901, NP_000892
- UniProt
- P08235
- Pathways
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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