SEC63 anticorps (C-Term)
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- Antigène Voir toutes SEC63 Anticorps
- SEC63 (SEC63 Homolog (SEC63))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SEC63 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- WWLYIADRKE QTLISMPYHV CTLKDTEEVE LKFPAPGKPG NYQYTVFLRS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against SEC63. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SEC63
- Top Product
- Discover our top product SEC63 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 760 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SEC63 (SEC63 Homolog (SEC63))
- Autre désignation
- SEC63 (SEC63 Produits)
- Synonymes
- anticorps DNAJC23, anticorps ERdj2, anticorps PRO2507, anticorps SEC63L, anticorps 5730478J10Rik, anticorps AI649014, anticorps AW319215, anticorps SEC63-like, anticorps zgc:92718, anticorps SEC63 homolog, protein translocation regulator, anticorps SEC63-like (S. cerevisiae), anticorps SEC63 homolog, protein translocation regulator L homeolog, anticorps SEC63, anticorps Sec63, anticorps sec63, anticorps sec63.L
- Sujet
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: UBC, IRF1, SEC61B, SEC62, GSTK1,
Protein Size: 760 - Poids moléculaire
- 88 kDa
- ID gène
- 11231
- NCBI Accession
- NM_007214, NP_009145
- UniProt
- Q9UGP8
- Pathways
- ER-Nucleus Signaling
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