ST14 anticorps (C-Term)

N° du produit ABIN2773910

Détail du produit anti-ST14 anticorps

Antigène: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ST14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ST14. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ST14

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 855 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ST14 (ABIN2773910)

Landova Sulcova, Zahradnicek, Dumkova, Dosedelova, Krivanek, Hampl, Kavkova, Zikmund, Gregorovicova, Sedmera, Kaiser, Tucker, Buchtova: "Developmental mechanisms driving complex tooth shape in reptiles." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).

Détails sur ST14

Antigène: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Autre désignation: ST14 (ST14 Produits)

Synonymes: anticorps HAI, anticorps MT-SP1, anticorps MTSP1, anticorps PRSS14, anticorps SNC19, anticorps TADG15, anticorps TMPRSS14, anticorps XMT-SP1, anticorps hai, anticorps mt-sp1, anticorps mtsp1, anticorps prss14, anticorps snc19, anticorps st14, anticorps st14a, anticorps tadg15, anticorps tmprss1, anticorps Epithin, anticorps Prss14, anticorps Tmprss14, anticorps mCAP3, anticorps matriptase, anticorps suppression of tumorigenicity 14, anticorps suppression of tumorigenicity 14 L homeolog, anticorps suppression of tumorigenicity 14 (colon carcinoma), anticorps ST14, anticorps st14.L, anticorps St14

Sujet: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Alias Symbols: HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14
Protein Interaction Partner: UBC, RGS16, PDGFC, CDCP1, SPINT1, F2RL1, PLAU, HGF,
Protein Size: 855

Poids moléculaire: 95 kDa

ID gène: 6768

NCBI Accession: NM_021978

UniProt: Q9Y5Y6