NPRL2 anticorps (N-Term)
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- Antigène Voir toutes NPRL2 Anticorps
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NPRL2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TUSC4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TUSC4
- Top Product
- Discover our top product NPRL2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 380 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- Antigène
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- Autre désignation
- TUSC4 (NPRL2 Produits)
- Synonymes
- anticorps 2810446G01Rik, anticorps G21, anticorps NPR2L, anticorps Tusc4, anticorps npr2, anticorps npr2l, anticorps tusc4, anticorps NPR2, anticorps TUSC4, anticorps im:6900399, anticorps zgc:153630, anticorps nitrogen permease regulator-like 2, anticorps NPR2 like, GATOR1 complex subunit S homeolog, anticorps NPR2 like, GATOR1 complex subunit, anticorps NPR2-like, GATOR1 complex subunit, anticorps Nprl2, anticorps nprl2.S, anticorps NPRL2, anticorps nprl2
- Sujet
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TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
Protein Interaction Partner: UBC, HSP90AA1, CDKN1A, ANXA7, NPRL3, UBE2M, PRKAR1A,
Protein Size: 380 - Poids moléculaire
- 44 kDa
- ID gène
- 10641
- NCBI Accession
- NM_006545, NP_006536
- UniProt
- Q8WTW4
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