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NPRL2 anticorps (N-Term)

NPRL2 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2773969
  • Antigène Voir toutes NPRL2 Anticorps
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Épitope
    • 15
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 53
    • 31
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)
    Hôte
    • 50
    • 2
    • 1
    Lapin
    Clonalité
    • 53
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NPRL2 est non-conjugé
    Application
    • 44
    • 22
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against TUSC4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human TUSC4
    Top Product
    Discover our top product NPRL2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 380 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Antigène
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Autre désignation
    TUSC4 (NPRL2 Produits)
    Synonymes
    anticorps 2810446G01Rik, anticorps G21, anticorps NPR2L, anticorps Tusc4, anticorps npr2, anticorps npr2l, anticorps tusc4, anticorps NPR2, anticorps TUSC4, anticorps im:6900399, anticorps zgc:153630, anticorps nitrogen permease regulator-like 2, anticorps NPR2 like, GATOR1 complex subunit S homeolog, anticorps NPR2 like, GATOR1 complex subunit, anticorps NPR2-like, GATOR1 complex subunit, anticorps Nprl2, anticorps nprl2.S, anticorps NPRL2, anticorps nprl2
    Sujet
    TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
    Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
    Protein Interaction Partner: UBC, HSP90AA1, CDKN1A, ANXA7, NPRL3, UBE2M, PRKAR1A,
    Protein Size: 380
    Poids moléculaire
    44 kDa
    ID gène
    10641
    NCBI Accession
    NM_006545, NP_006536
    UniProt
    Q8WTW4
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