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Cortactin anticorps (N-Term)
CTTN
Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2774002
Détail du produit anti-Cortactin anticorps
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Antigène
Voir toutes Cortactin (CTTN) Anticorps
Cortactin (CTTN)
Épitope
Tous les épitopes à travers Cortactin Anticorps.
N-Term
Reactivité
Toutes les réactivités sur Cortactin Anticorps
Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
Hôte
Toutes les hôtes sur Cortactin Anticorps
Lapin
Clonalité
Toutes les clonalités sur Cortactin Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Cortactin Anticorps
Cet anticorp Cortactin est non-conjugé
Application
Tous les applications à travers Cortactin Anticorps.
Western Blotting (WB)
Séquence
KSAVGFDYQG KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE
Homologie
Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
Attributs du produit
This is a rabbit polyclonal antibody against CTTN. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTTN
Top Product
Discover our top product CTTN Anticorps primaire
Alternatives
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Information d'application
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Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur Cortactin
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Antigène
Cortactin (CTTN)
Autre désignation
CTTN (CTTN Produits )
Synonymes
anticorps EMS1, anticorps 1110020L01Rik, anticorps Ems1, anticorps Cttnb, anticorps CG3637, anticorps Dmel\CG3637, anticorps cortactin, anticorps cttn, anticorps CTTN1, anticorps P85.25, anticorps Cttn, anticorps ems1, anticorps CTTN, anticorps cortactin, anticorps CG3637 gene product from transcript CG3637-RD, anticorps cortactin S homeolog, anticorps cortactin L homeolog, anticorps src substrate cortactin, anticorps Src substrate cortactin, anticorps CTTN, anticorps Cttn, anticorps Cortactin, anticorps cttn.S, anticorps cttn.L, anticorps cttn, anticorps CpipJ_CPIJ006351, anticorps Bm1_57220, anticorps LOC100533277
Sujet
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. Alias Symbols: EMS1 Protein Interaction Partner: SPRR2A, CDC37, CTTN, UBC, NEDD8, RPA3, RPA2, RPA1, VTA1, GSPT2, ATG7, UGDH, ME1, IDE, GSPT1, GARS, CTNNA1, ATP6V1C1, APEH, STAT1, SSB, SNX2, SNX1, SHMT2, SHMT1, SARS, RDX, ACTR2, NPM1, LMNA, ACTG1, ACTR3, PAN2, ATF2, DNM2, NCF1, Mbp, ASAP1, CORO1B, SDHAF2 Protein Size: 634
Poids moléculaire
69 kDa
ID gène
2017
NCBI Accession
NM_138565 , NP_612632
Pathways
Signalisation MAPK
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