KPNA4 anticorps (N-Term)

N° du produit ABIN2774081

Détail du produit anti-KPNA4 anticorps

Antigène: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA4 est non-conjugé

Application: Western Blotting (WB)

Séquence: KNKRDEHLLK RRNVPHEDIC EDSDIDGDYR VQNTSLEAIV QNASSDNQGI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KPNA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 521 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KPNA4

Antigène: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Autre désignation: KPNA4 (KPNA4 Produits)

Synonymes: anticorps IPOA3, anticorps QIP1, anticorps SRP3, anticorps 6, anticorps ATIMPALPHA3, anticorps IMPA-3, anticorps IMPORTIN ALPHA 3, anticorps IMPORTIN ALPHA ISOFORM 3, anticorps MODIFIER OF SNC1, anticorps T10M13.16, anticorps T10M13_16, anticorps LOC100224013, anticorps 1110058D08Rik, anticorps importin, anticorps ipoa3, anticorps qip1, anticorps srp3, anticorps impa3, anticorps wu:fa56d07, anticorps wu:fa66g10, anticorps wu:fe14c04, anticorps wu:fi04h11, anticorps wu:fi19b05, anticorps karyopherin subunit alpha 4, anticorps ARM repeat superfamily protein, anticorps importin alpha 3, anticorps karyopherin (importin) alpha 4, anticorps karyopherin alpha 4 (importin alpha 3) S homeolog, anticorps karyopherin alpha 4 (importin alpha 3), anticorps KPNA4, anticorps MOS6, anticorps LOC100533341, anticorps Kpna4, anticorps kpna4.S, anticorps kpna4

Sujet: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. KPNA4 shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA3, MGC12217, MGC26703, QIP1, SRP3
Protein Interaction Partner: HNRNPC, CYHR1, MAT2B, NUP50, PLAA, HSF1, UBC, LIN28A, rev, KPNA2, ACLY, SOX2, HDAC1, NACC1, CSNK2A1, AICDA, CBX5, APP, CUL3, DAXX, PARD3, ELAVL1, EXO1, CDKN1B, CUL4B, Ranbp2, Mki67, CTCF, MYC, TP53, H3F3A, RCC1, RAC1, RECQL, TGM2, KPNB1, CSE1L, ARRB2,
Protein Size: 521

Poids moléculaire: 58 kDa

ID gène: 3840

NCBI Accession: NM_002268, NP_002259

UniProt: O00629

Pathways: Protein targeting to Nucleus