ANKRD15 anticorps (C-Term)

N° du produit ABIN2774113

Détail du produit anti-ANKRD15 anticorps

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB)

Séquence: STALSIALEA GHKDIAVLLY AHVNFAKAQS PGTPRLGRKT SPGPTHRGSF

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KANK1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human KANK1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1 (ANKRD15 Produits)

Sujet: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.
Alias Symbols: KANK, CPSQ2, ANKRD15
Protein Size: 330

Poids moléculaire: 36 kDa

ID gène: 23189

NCBI Accession: NM_001256876, NP_001243805

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization