COPS4 anticorps (Middle Region)
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- Antigène Voir toutes COPS4 Anticorps
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp COPS4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YKLETYLKIA RLYLEDDDPV QAEAYINRAS LLQNESTNEQ LQIHYKVCYA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against COPS4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human COPS4
- Top Product
- Discover our top product COPS4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 406 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- Antigène
- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
- Autre désignation
- COPS4 (COPS4 Produits)
- Sujet
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COPS4 is one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10899, MGC15160, CSN4
Protein Interaction Partner: USHBP1, GPS1, UBC, Skp2, PRMT5, KPNA2, HSP90AB1, EPB41L2, EPB41L1, CAST, WDR77, ENAH, DCAF8, COPS5, STIP1, COPS6, YWHAQ, FOS, COPS8, COPS7A, FBXO6, BAG3, FBXW4, vpr, IRF5, COPS7B, COPS2, COPS3, TOR1AIP2, LRR1, FBXO17, DCAF11, DDA1, RFWD2, KLHL42, GRK5, DD
Protein Size: 406 - Poids moléculaire
- 46 kDa
- ID gène
- 51138
- NCBI Accession
- NM_016129, NP_057213
- UniProt
- Q9BT78
- Pathways
- Cycle Cellulaire
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