NFKBIZ anticorps (C-Term)
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- Antigène Voir toutes NFKBIZ Anticorps
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Chévre, Cobaye, Mouton, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFKBIZ est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VRLLMRKGAD PSTRNLENEQ PVHLVPDGPV GEQIRRILKG KSIQQRAPPY
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
- Attributs du produit
- This is a rabbit polyclonal antibody against Nfkbiz. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product NFKBIZ Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 728 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
- Autre désignation
- Nfkbiz (NFKBIZ Produits)
- Synonymes
- anticorps RGD1310834, anticorps NFKBIZ, anticorps MAIL, anticorps AA408868, anticorps INAP, anticorps Mail, anticorps IKBZ, anticorps NFKB inhibitor zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta, anticorps Nfkbiz, anticorps NFKBIZ, anticorps nfkbiz
- Sujet
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Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Alias Symbols: AA408868, INAP, Mail
Protein Interaction Partner: Nfkb2, Nfkb1, Ikbkg, Elf5, Ehf, Il6,
Protein Size: 728 - Poids moléculaire
- 80 kDa
- ID gène
- 80859
- NCBI Accession
- NM_030612, NP_085115
- UniProt
- Q9EST8
- Pathways
- Signalisation NF-kappaB
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