TFAP2B anticorps (N-Term)
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- Antigène Voir toutes TFAP2B Anticorps
- TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TFAP2B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MHSPPRDQAA IMLWKLVENV KYEDIYEDRH DGVPSHSSRL SQLGSVSQGP
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TFAP2B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2B
- Top Product
- Discover our top product TFAP2B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 460 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))
- Autre désignation
- TFAP2B (TFAP2B Produits)
- Synonymes
- anticorps TFAP2B, anticorps AP-2B, anticorps Tcfap2b, anticorps AP2, anticorps si:dkey-5e16.1, anticorps zgc:110163, anticorps AP-1beta1, anticorps AP-2beta, anticorps AP-beta1, anticorps AP1beta1, anticorps AP2beta2, anticorps BAD1, anticorps BAP, anticorps Beta-adaptin, anticorps CG12532, anticorps Dmel\\CG12532, anticorps bap, anticorps beta1/2, anticorps cg12532, anticorps AI606113, anticorps AP-2(beta), anticorps E130018K07Rik, anticorps AP2-B, anticorps ap-2b, anticorps ap2-b, anticorps tfap2beta, anticorps transcription factor AP-2 beta, anticorps beta-adaptin, anticorps putative beta-adaptin, anticorps Adaptor Protein complex 1/2, beta subunit, anticorps transcription factor AP-2 beta L homeolog, anticorps TFAP2B, anticorps Tfap2b, anticorps tfap2b, anticorps Tc00.1047053509799.10, anticorps Tc00.1047053506247.200, anticorps LINJ_36_7080, anticorps LBRM_35_7120, anticorps LMJF_36_6770, anticorps Tcfap2b, anticorps AP-1-2beta, anticorps Tsp_09571, anticorps tfap2b.L
- Sujet
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TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes. This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 c
Alias Symbols: AP-2B, AP2-B, MGC21381
Protein Interaction Partner: YEATS4, UBC, KCTD1, UBE2I, SUMO1, SSBP4, LZTR1, VPS11, HIST1H2AC, CITED4, MYC, CITED2, CITED1,
Protein Size: 460 - Poids moléculaire
- 50 kDa
- ID gène
- 7021
- NCBI Accession
- NM_003221, NP_003212
- UniProt
- Q92481
- Pathways
- Carbohydrate Homeostasis, Synaptic Membrane
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