Adenylosuccinate Lyase anticorps (Middle Region)

N° du produit ABIN2774275

Détail du produit anti-Adenylosuccinate Lyase anticorps

Antigène: Adenylosuccinate Lyase (ADSL)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Cheval, Boeuf (Vache), Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ADSL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 484 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL (ADSL Produits)

Synonymes: anticorps fi60b04, anticorps zgc:56061, anticorps wu:fi60b04, anticorps MGC53383, anticorps MGC69239, anticorps adsL, anticorps F15C21.8, anticorps F15C21_8, anticorps AMPS, anticorps ASASE, anticorps ASL, anticorps Adl, anticorps Asl, anticorps purB, anticorps adenylosuccinate lyase, anticorps adenylosuccinate lyase L homeolog, anticorps adenylosuccinase; ASL, anticorps Adenylosuccinate lyase, anticorps L-Aspartase-like family protein, anticorps ADSL, anticorps adsl, anticorps adsl.L, anticorps ASL, anticorps purB, anticorps purB,adsL, anticorps Mrub_2293, anticorps MMAH_RS02975, anticorps Arnit_0089, anticorps Mesil_1058, anticorps Slip_0597, anticorps Trad_2452, anticorps Deba_0652, anticorps Toce_1174, anticorps Acear_2324, anticorps Igag_0272, anticorps Saut_2156, anticorps Fbal_1996, anticorps Ndas_2434, anticorps Ilyop_0196, anticorps Lbys_2961, anticorps MFER_RS02920, anticorps Palpr_2192, anticorps Calni_0061, anticorps Ftrac_3746, anticorps AT1G36280, anticorps Olsu_1764, anticorps Adsl

Sujet: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMPS, ASASE, ASL
Protein Interaction Partner: CALCOCO2, REL, UBC, PDE12, BTF3L4, NPLOC4, EHD4, UBQLN2, NT5C2, WDR4, PAIP1, PLIN3, SAE1, OXSR1, API5, XPNPEP1, WARS, RAD23B, TWF1, DNAJB1, GTF2I, EIF1AX, DRG2, CTSC, NOV, TYMS, SUMO1, DDA1, USP15, USP4,
Protein Size: 484

Poids moléculaire: 55 kDa

ID gène: 158

NCBI Accession: NM_000026, NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process