LGMN anticorps (Middle Region)
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- Antigène Voir toutes LGMN Anticorps
- LGMN (Legumain (LGMN))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Mouton, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LGMN est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ESSYACYYDE KRSTYLGDWY SVNWMEDSDV EDLTKETLHK QYHLVKSHTN
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against LGMN. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human LGMN
- Top Product
- Discover our top product LGMN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 433 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LGMN (Legumain (LGMN))
- Autre désignation
- LGMN (LGMN Produits)
- Synonymes
- anticorps AEP, anticorps LGMN1, anticorps PRSC1, anticorps AI746452, anticorps AU022324, anticorps Prsc1, anticorps MGC64351, anticorps cb173, anticorps cb460, anticorps sb:cb173, anticorps zgc:76953, anticorps wu:fa98g05, anticorps wu:fj92g08, anticorps lgmn, anticorps MGC88980, anticorps DELTA VACUOLAR PROCESSING ENZYME, anticorps DELTAVPE, anticorps delta vacuolar processing enzyme, anticorps legumain, anticorps legumain L homeolog, anticorps delta vacuolar processing enzyme, anticorps Legumain, anticorps LGMN, anticorps Lgmn, anticorps lgmn.L, anticorps lgmn, anticorps DELTA-VPE, anticorps MBOO_RS07785, anticorps Odosp_3582, anticorps LOC569153
- Sujet
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This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.
Alias Symbols: AEP, LGMN1, PRSC1
Protein Interaction Partner: USP17L2, TRAF6, USP17L9P, SUMO1, UBC, NEDD8, LAMC3, ACIN1, IGF2BP3, HNRNPR, FBXO6, ISG15, LGMN,
Protein Size: 433 - Poids moléculaire
- 48 kDa
- ID gène
- 5641
- NCBI Accession
- NM_005606, NP_005597
- UniProt
- Q99538
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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