POF1B anticorps (C-Term)
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- Antigène Voir toutes POF1B Anticorps
- POF1B (Premature Ovarian Failure, 1B (POF1B))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POF1B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MEKDREICRL RSQLNQYHKD VSKREGSCSD FQFKLHELTS LLEEKDSLIK
- Homologie
- Cow: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against POF1B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human POF1B
- Top Product
- Discover our top product POF1B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 589 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- POF1B (Premature Ovarian Failure, 1B (POF1B))
- Autre désignation
- POF1B (POF1B Produits)
- Synonymes
- anticorps RGD1560798, anticorps 2310066B14Rik, anticorps POF, anticorps POF2B, anticorps POF1B, actin binding protein, anticorps premature ovarian failure 1B, anticorps Pof1b, anticorps POF1B
- Sujet
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Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
Alias Symbols: FLJ22792, POF, POF2B
Protein Interaction Partner: ESR1, COPS5, UBC, Cdk1, Akap12, Fam134a, Lyplal1, Tpr, UCHL5,
Protein Size: 589 - Poids moléculaire
- 65 kDa
- ID gène
- 79983
- NCBI Accession
- NM_024921, NP_079197
- UniProt
- Q8WVV4
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