EFTUD1 anticorps (C-Term)

N° du produit ABIN2774502

Détail du produit anti-EFTUD1 anticorps

Antigène: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFTUD1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TTEEEYLHFG EKADSENQAR KYMNAVRKRK GLYVEEKIVE HAEKQRTLSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human EFTUD1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1069 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EFTUD1

Antigène: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Autre désignation: EFTUD1 (EFTUD1 Produits)

Sujet: EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Alias Symbols: FAM42A, HsT19294, RIA1
Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
Protein Size: 1069

Poids moléculaire: 117 kDa

ID gène: 79631

NCBI Accession: NM_001040610, NP_001035700

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly