RNF139 anticorps (N-Term)
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- Antigène Voir toutes RNF139 Anticorps
- RNF139 (Ring Finger Protein 139 (RNF139))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RNF139 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SQRSLFKFYT YSSAFLLAAT SVLVNYYASL HIDFYGAYNT SAFGIELLPR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RNF139. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RNF139
- Top Product
- Discover our top product RNF139 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 664 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RNF139 (Ring Finger Protein 139 (RNF139))
- Autre désignation
- RNF139 (RNF139 Produits)
- Synonymes
- anticorps HRCA1, anticorps RCA1, anticorps TRC8, anticorps 4930555P18Rik, anticorps zgc:175173, anticorps rnf139, anticorps ring finger protein 139, anticorps ring finger protein 139 S homeolog, anticorps RNF139, anticorps Rnf139, anticorps rnf139, anticorps rnf139.S
- Sujet
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RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Alias Symbols: HRCA1, MGC31961, RCA1, TRC8
Protein Interaction Partner: HM13, HLA-C, UBE2G2, AUP1, UBC, INSIG1, HMGCR, INSIG2, TMUB1, ERLIN2, ERLIN1, SCAP, SEC24B, SREBF2, EIF3A, UBE2U, UBE2Z, UBE2H, COPS5, VHL,
Protein Size: 664 - Poids moléculaire
- 76 kDa
- ID gène
- 11236
- NCBI Accession
- NM_007218, NP_009149
- UniProt
- Q8WU17
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