FBXL5 anticorps (Middle Region)

N° du produit ABIN2774689

Détail du produit anti-FBXL5 anticorps

Antigène: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VHWARGDWYS GPATELDTEP DDEWVKNRKD ESRAFHEWDE DADIDESEES

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXL5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXL5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 691 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXL5

Antigène: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Autre désignation: FBXL5 (FBXL5 Produits)

Synonymes: anticorps fbxl5, anticorps MGC53238, anticorps FBXL5, anticorps FBL4, anticorps FBL5, anticorps FLR1, anticorps Fbl4, anticorps Fir4, anticorps wu:fb52d06, anticorps F-box and leucine rich repeat protein 5, anticorps F-box and leucine-rich repeat protein 5 S homeolog, anticorps F-box and leucine-rich repeat protein 5 L homeolog, anticorps F-box and leucine-rich repeat protein 5, anticorps FBXL5, anticorps fbxl5.S, anticorps fbxl5.L, anticorps fbxl5, anticorps Fbxl5

Sujet: FBXL5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL5 belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: FBL4, FBL5, FLR1
Protein Interaction Partner: NABP2, CUL1, SNAI1, SKP1, FBXL5, HERC2, UBC, IREB2, ACO1, RBX1, MUS81, MMS19, FAM96B, ORC4, EP300, SMURF1, BTG1, COPS5, PLK1, CSNK2B, DCTN1,
Protein Size: 691

Poids moléculaire: 76 kDa

ID gène: 26234

NCBI Accession: NM_012161, NP_036293

UniProt: Q9UKA1

Pathways: Transition Metal Ion Homeostasis