RNF128 anticorps (C-Term)

N° du produit ABIN2774780

Détail du produit anti-RNF128 anticorps

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF128 est non-conjugé

Application: Western Blotting (WB)

Séquence: LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 428 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF128

Antigène: RNF128 (Ring Finger Protein 128 (RNF128))

Autre désignation: RNF128 (RNF128 Produits)

Synonymes: anticorps rnf128, anticorps wu:fb57h05, anticorps zgc:77843, anticorps 1300002C13Rik, anticorps AI987883, anticorps GRAIL, anticorps Greul1, anticorps RGD1566282, anticorps grail, anticorps greul1, anticorps ring finger protein 128a, anticorps ring finger protein 128, E3 ubiquitin protein ligase, anticorps ring finger protein 128, anticorps ring finger protein 128, E3 ubiquitin protein ligase L homeolog, anticorps rnf128a, anticorps RNF128, anticorps Rnf128, anticorps rnf128.L

Sujet: RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 428

Poids moléculaire: 47 kDa

ID gène: 79589

NCBI Accession: NM_194463, NP_919445

UniProt: Q8TEB7