STUB1 anticorps (N-Term)

N° du produit ABIN2774916

Détail du produit anti-STUB1 anticorps

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STUB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MKGKEEKEGG ARLGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against STUB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STUB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 303 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STUB1

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Autre désignation: STUB1 (STUB1 Produits)

Synonymes: anticorps CHIP, anticorps HSPABP2, anticorps NY-CO-7, anticorps SDCCAG7, anticorps UBOX1, anticorps 0610033N24Rik, anticorps 2210017D18Rik, anticorps 2310040B03Rik, anticorps AW046544, anticorps Chip, anticorps wu:fc22f04, anticorps zgc:56076, anticorps STUB1, anticorps chip, anticorps ATCHIP, anticorps CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN, anticorps carboxyl terminus of HSC70-interacting protein, anticorps STIP1 homology and U-box containing protein 1, anticorps STIP1 homology and U-Box containing protein 1, anticorps STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog, anticorps STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase, anticorps STIP1 homology and U box-containing protein 1, anticorps carboxyl terminus of HSC70-interacting protein, anticorps STUB1, anticorps Stub1, anticorps stub1, anticorps stub1.L, anticorps LOC100282870, anticorps CHIP

Sujet: STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
Alias Symbols: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1
Protein Interaction Partner: HSP90AA1, HSPA8, PCSK9, OLFM3, ATCAY, CCL28, UBE2Q1, TXN2, RUSC1, HSPA1B, FMR1, ERN1, STUB1, UBE2V1, UBE2N, UBE2D3, UBE2D1, UBC, TP53, MAPT, MAP3K11, SNAI2, BAG1, HSPA4L, CDC37, DNAJB6, BAG2, BAG3, BAG4, MLF2, HSP90AB1, HSPA4, HSPA2, HSPA1L, ENDOG, TXLNG,
Protein Size: 303

Poids moléculaire: 35 kDa

ID gène: 10273

NCBI Accession: NM_005861, NP_005852

UniProt: Q9UNE7

Pathways: Regulation of Hormone Metabolic Process, Response to Water Deprivation