AKAP5 anticorps (Middle Region)
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- Antigène Voir toutes AKAP5 Anticorps
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
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Épitope
- Middle Region
- Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Saccharomyces cerevisiae, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AKAP5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE
- Homologie
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Yeast: 82%
- Attributs du produit
- This is a rabbit polyclonal antibody against AKAP5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human AKAP5
- Top Product
- Discover our top product AKAP5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 427 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
- Autre désignation
- AKAP5 (AKAP5 Produits)
- Synonymes
- anticorps AKAP5, anticorps AKAP75, anticorps AKAP79, anticorps H21, anticorps AKAP, anticorps P75, anticorps 3526401B18Rik, anticorps AKAP 150, anticorps AKAP-5, anticorps AKAP150, anticorps BB098886, anticorps Gm258, anticorps P150, anticorps Akap79, anticorps A kinase (PRKA) anchor protein 5, anticorps A-kinase anchoring protein 5, anticorps AKAP5, anticorps Akap5
- Classe de substances
- Viral Protein
- Sujet
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AKAP75, AKAP79, H21
Protein Interaction Partner: PRKACB, PRKACA, UBC, PRKCA, CALM1, GABRB1, GABRB3, IQGAP1, DLG4, DLG1, KCNJ2, PRKAR2B, PRKAR2A, RET, PPP3CA, ADRB2, Gria1, Grin2b,
Protein Size: 427 - Poids moléculaire
- 47 kDa
- ID gène
- 9495
- NCBI Accession
- NM_004857, NP_004848
- UniProt
- P24588
- Pathways
- cAMP Metabolic Process
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