DHX9 anticorps (N-Term)

N° du produit ABIN2775181

Détail du produit anti-DHX9 anticorps

Antigène: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GLHGNWTLEN AKARLNQYFQ KEKIQGEYKY TQVGPDHNRS FIAEMTIYIK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DHX9. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1279 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DHX9 (ABIN2775181)

Kawai, Amano: "BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex." dans: The Journal of cell biology, Vol. 197, Issue 2, pp. 201-8, (2012) (PubMed).

Détails sur DHX9

Antigène: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Autre désignation: DHX9 (DHX9 Produits)

Synonymes: anticorps DDX9, anticorps LKP, anticorps NDH2, anticorps NDHII, anticorps RHA, anticorps AI326842, anticorps Ddx9, anticorps HEL-5, anticorps mHEL-5, anticorps DExH-box helicase 9, anticorps DEAH-box helicase 9 L homeolog, anticorps DEAH (Asp-Glu-Ala-His) box polypeptide 9, anticorps DHX9, anticorps dhx9.L, anticorps Dhx9

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX9 is a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.
Alias Symbols: DDX9, LKP, NDH II, NDHII, RHA, NDH2
Protein Interaction Partner: UBC, PA2G4, FBXW11, AURKA, SUMO2, SUMO3, MDM2, CEP250, SART3, STAU1, IVNS1ABP, EIF2AK2, LGR4, SUMO1, WWOX, RPA3, RPA2, RPA1, SUZ12, EED, EZH2, RNF2, rev, DDX1, APBB1, ABCF1, FLII, PRPF40A, C14orf166, RTCB, RPL26L1, NELFB, HNRNPA0, IGF2BP3, LRRFIP1, MAP7,
Protein Size: 1279

Poids moléculaire: 141 kDa

ID gène: 1660

NCBI Accession: NM_001357, NP_001348

UniProt: Q08211