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DDX21 anticorps (N-Term)

DDX21 Reactivité: Humain, Rat, Cheval, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775197
  • Antigène Voir toutes DDX21 Anticorps
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Épitope
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 37
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Cheval, Saccharomyces cerevisiae
    Hôte
    • 37
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DDX21 est non-conjugé
    Application
    • 26
    • 14
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MPGKLRSDAG LESDTAMKKG ETLRKQTEEK EKKEKPKSDK TEEIAEEEET
    Homologie
    Horse: 79%, Human: 100%, Rat: 91%, Yeast: 83%
    Attributs du produit
    This is a rabbit polyclonal antibody against DDX21. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human DDX21
    Top Product
    Discover our top product DDX21 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 783 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • De Wever, Lloyd, Nasa, Nimick, Trinkle-Mulcahy, Gourlay, Morrice, Moorhead: "Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39510, (2012) (PubMed).

    Naji, Ambrus, Cimerman?i?, Reyes, Johnson, Filbrandt, Huber, Vesely, Krogan, Yates, Saphire, Gerace: "Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production." dans: Molecular & cellular proteomics : MCP, Vol. 11, Issue 4, pp. M111.015313, (2012) (PubMed).

  • Antigène
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Autre désignation
    DDX21 (DDX21 Produits)
    Synonymes
    anticorps MGC130693, anticorps DDX21, anticorps cb960, anticorps wu:fi30c07, anticorps wu:fi34d08, anticorps GUA, anticorps GURDB, anticorps RH-II/GU, anticorps RH-II/GuA, anticorps Ddx21a, anticorps AI255159, anticorps AL022742, anticorps D10Ertd645e, anticorps D10Wsu42e, anticorps DEAD-box helicase 21 L homeolog, anticorps DExD-box helicase 21, anticorps DEAD-box helicase 21, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 21, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 21, anticorps ddx21.L, anticorps DDX21, anticorps ddx21, anticorps Ddx21
    Sujet
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
    Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA
    Protein Interaction Partner: HUWE1, PA2G4, KPNA3, CEP250, SUMO2, SUMO3, STAU1, IVNS1ABP, UBC, MDM2, LGR4, SUMO1, ERG, WWOX, EED, rev, SRPK2, SRPK3, FBXO6, TARDBP, LYN, AICDA, PAN2, vif, WHSC1, VCAM1, ITGA4, IL7R, FN1, CSNK2A1, YWHAE, SMURF1, H2AFX, APTX, ESR1, FTSJ3, PCDHA2, RRP7A, R
    Protein Size: 783
    Poids moléculaire
    86 kDa
    ID gène
    9188
    NCBI Accession
    NM_004728, NP_004719
    UniProt
    Q9NR30
    Pathways
    SARS-CoV-2 Protein Interactome
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