DNA Helicase B anticorps (N-Term)

N° du produit ABIN2775262

Détail du produit anti-DNA Helicase B anticorps

Antigène: DNA Helicase B (HELB)

Épitope: N-Term

Reactivité: Humain, Porc, Boeuf (Vache), Cobaye, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNA Helicase B est non-conjugé

Application: Western Blotting (WB)

Séquence: FGRFPITGAW WRVKVQVKPV VGSRSYQYQV QGFPSYFLQS DMSPPNQKHI

Homologie: Cow: 86%, Guinea Pig: 79%, Human: 100%, Pig: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HELB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HELB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1087 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DNA Helicase B (ABIN2775262)

Taneja, Gu, Peng, Carrick, Uchiumi, Ott, Gustafson, Podust, Fanning: "A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication." dans: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40853-61, (2002) (PubMed).

Détails sur DNA Helicase B

Antigène: DNA Helicase B (HELB)

Autre désignation: HELB (HELB Produits)

Sujet: The protein encoded by this gene is a DNA helicase. A dominant-negative mutant of this protein blocks chromosomal DNA replication and suggests that its function is required for S phase entry.
Alias Symbols: hDHB
Protein Interaction Partner: UBC, PMS1, POLA2, POLA1, RPA1,
Protein Size: 1087

Poids moléculaire: 120 kDa

ID gène: 92797

NCBI Accession: NM_033647, NP_387467

UniProt: Q8NG08