Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

alpha Actinin 4 anticorps (C-Term)

ACTN4 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775289
  • Antigène Voir toutes alpha Actinin 4 (ACTN4) Anticorps
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Épitope
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 91
    • 49
    • 45
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)
    Hôte
    • 84
    • 7
    Lapin
    Clonalité
    • 72
    • 18
    Polyclonal
    Conjugué
    • 55
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp alpha Actinin 4 est non-conjugé
    Application
    • 68
    • 31
    • 26
    • 17
    • 16
    • 15
    • 14
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    DVENDRQGEA EFNRIMSLVD PNHSGLVTFQ AFIDFMSRET TDTDTADQVI
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against ACTN4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human ACTN4
    Top Product
    Discover our top product ACTN4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 911 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Antigène
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Autre désignation
    ACTN4 (ACTN4 Produits)
    Synonymes
    anticorps fsgs, anticorps fsgs1, anticorps C77391, anticorps ACTININ-4, anticorps FSGS, anticorps FSGS1, anticorps wu:fb53f05, anticorps zgc:63508, anticorps actinin alpha 4, anticorps actinin, alpha 4, anticorps actinin alpha 4 S homeolog, anticorps actn4, anticorps ACTN4, anticorps Actn4, anticorps actn4.S
    Sujet
    Alpha actinins belong to the spectrin superfamily which is a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in its gene have been associated with focal and segmental glomerulosclerosis.Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
    Alias Symbols: DKFZp686K23158, FSGS, FSGS1, ACTININ-4
    Protein Interaction Partner: MYOZ2, HUWE1, UBC, BMP7, ACTN3, SUMO2, SUMO3, GNB2, SUMO1, NEDD8, MDM2, HGS, SF3A3, VCP, CDKN2A, ACTN1, PDLIM1, UBD, IGSF8, ICAM1, CD81, SVIL, Fcho2, POT1, VCAM1, TXN, RPS27, MAPK7, KPNA2, ITGA4, FN1, ESR1, CDH1, TRAF3IP1, FMNL1, NOS3, ACTN2, UBASH3B, SHC
    Protein Size: 911
    Poids moléculaire
    105 kDa
    ID gène
    81
    NCBI Accession
    NM_004924, NP_004915
    UniProt
    O43707
    Pathways
    Proton Transport
Vous êtes ici:
Support technique