NAMPT anticorps (C-Term)

N° du produit ABIN2775322

Détail du produit anti-NAMPT anticorps

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA QLNIELEAAH

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PBEF1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 491 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NAMPT (ABIN2775322)

Xia, Weisenburger, Koch, Burkart, Reifenberg, Förstermann, Li: "Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight." dans: British journal of pharmacology, Vol. 174, Issue 20, pp. 3443-3453, (2017) (PubMed).

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: PBEF1 (NAMPT Produits)

Synonymes: anticorps 1110035O14Rik, anticorps PBEF, anticorps PBEF1, anticorps VF, anticorps VISFATIN, anticorps AI314458, anticorps AI480535, anticorps NAmPRTase, anticorps Pbef, anticorps Pbef1, anticorps Visfatin, anticorps visfatin, anticorps pbef, anticorps pbef1, anticorps nicotinamide phosphoribosyltransferase, anticorps Nicotinamide phosphoribosyltransferase, anticorps nicotinamide phosphoribosyltransferase S homeolog, anticorps NAMPT, anticorps Nampt, anticorps nampt, anticorps Smon_0680, anticorps Mrub_2845, anticorps Cseg_3704, anticorps BC1002_3997, anticorps Ftrac_2686, anticorps Varpa_5681, anticorps Celal_3900, anticorps Deima_0880, anticorps BC1001_3724, anticorps Celly_1696, anticorps Clole_1542, anticorps Tsp_05934, anticorps nampt.S

Sujet: PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Alias Symbols: 1110035O14Rik, DKFZP666B131, MGC117256, NAMPT, PBEF, VF, PBEF1, VISFATIN
Protein Interaction Partner: UBC, NEDD8, NDRG1, CTSA, PEPD, MVD, GSR, ASS1, ANXA6, CD81, AKT2, ADORA2A, IFITM3, ND1, GGT1, FTL, CUL5, DDA1, GBAS, FANCA,
Protein Size: 491

Poids moléculaire: 54 kDa

ID gène: 10135

NCBI Accession: NM_005746, NP_005737

UniProt: P43490